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Development of a Clinic-Based, Sociostructural Intervention to Improve the Provision of Pre-Exposure Prophylaxis for Cisgender Women: Formative Study Using the Assessment, Decision, Adaptation, Production, Topical Experts, Integration, Training, and Testing (ADAPT-ITT) Framework

Development of a Clinic-Based, Sociostructural Intervention to Improve the Provision of Pre-Exposure Prophylaxis for Cisgender Women: Formative Study Using the Assessment, Decision, Adaptation, Production, Topical Experts, Integration, Training, and Testing (ADAPT-ITT) Framework

Given the critical role of providers as both Pr EP educators and gatekeepers, we previously developed and tested HIV Pr EP Services for Urban Women, a clinic-level educational intervention, which used a clinic-wide training and a provider toolkit to promote the provision of universal Pr EP services.

Rachel Katherine Scott, Shawnika J Hull, Deanna Kerrigan, Mandi Pratt-Chapman, Tara Mathias-Prabhu, Jennifer Zack, Michelle Xu, Marisa Sadauskas, Patricia L Moriarty, Tranessa L Hanson, Hannah Arem

JMIR Form Res 2025;9:e75922

Stakeholder Perspectives on Trustworthy AI for Parkinson Disease Management Using a Cocreation Approach: Qualitative Exploratory Study

Stakeholder Perspectives on Trustworthy AI for Parkinson Disease Management Using a Cocreation Approach: Qualitative Exploratory Study

Workshops are considered a key component of the cocreation process, enabling active participation and engagement, allowing individuals to contribute their unique insights, and fostering a sense of ownership. In addition, workshops provide a platform for immediate feedback and iteration, ensuring that solutions are responsive to participants’ input and preferences [24].

Beatriz Alves, Ghada Alhussein, Sara Riggare, Therese Scott Duncan, Ali Saad, David M Lyreskog, Christos Chatzichristos, Ioannis Gerasimou, Stelios Hadjidimitriou, Leontios J Hadjileontiadis, Sofia B Dias, AI-PROGNOSIS Consortium

J Med Internet Res 2025;27:e73710

Variability in the Diagnosis and Treatment of Interstitial Cystitis/Bladder Pain Syndrome: Internet Survey

Variability in the Diagnosis and Treatment of Interstitial Cystitis/Bladder Pain Syndrome: Internet Survey

Emerging evidence suggests a potential variation in the natural history of IC/BPS across racial and ethnic groups. For instance, Black individuals with IC/BPS report a greater degree of urinary urgency compared to their White counterparts and are more likely to be diagnosed at a younger age [19,20].

Eleanora Melkonian, A Leigh Garrett, Erika Kline, Pressley Smith, Madelyn Wiesenhahn, Jeanette Petit, Alison Swierczynski, Carley Zhou, Stuart B Bauer, Rosalyn Adam, Kamil E Barbour, Sonja I Ziniel, Catherine A Brownstein

JMIR Form Res 2025;9:e70813

Usability Testing of an Internet-Based Responsive Parenting Program for Caregivers of Young Survivors of Childhood Cancer Living in Rural and Appalachian Communities: Mixed Methods Study

Usability Testing of an Internet-Based Responsive Parenting Program for Caregivers of Young Survivors of Childhood Cancer Living in Rural and Appalachian Communities: Mixed Methods Study

Survival rates for most types of childhood cancers have fortunately risen to over 80%, resulting in a growing cohort of nearly half a million childhood cancer survivors in the United States [1]. However, life-saving cancer treatments, such as chemotherapy and radiation, can be detrimental to a child’s development and lead to a host of chronic health needs for up to two-thirds of survivors, termed late effects [1].

Emily L Moscato, Eva Darow, Jessica Quach, Adrien M Winning, Matthew Schmidt, Shari L Wade, Cynthia A Gerhardt, Emre Sezgin

JMIR Pediatr Parent 2025;8:e70055

Experiences With a Multicomponent Digital Behavioral Pain Management Intervention for Adults With Sickle Cell Disease: Qualitative Analysis of the CaRISMA Trial

Experiences With a Multicomponent Digital Behavioral Pain Management Intervention for Adults With Sickle Cell Disease: Qualitative Analysis of the CaRISMA Trial

The Ca RISMA trial enrolled adults with SCD who reported chronic pain (ie, pain at least 4 days a week over the past 3 months or longer). Participants of the Ca RISMA trial were recruited from 7 comprehensive sickle cell centers and from 4 community-based organizations, either virtually or in person. Participants were randomized 1:1 to either the digital CBT or Education arm. Both arms had access to a health coach and a chat system via a chatbot.

Olubusola B Oluwole, Lakeya S McGill, Kadeem Gayle, Julia A O'Brien, Kaleab Z Abebe, Charles R Jonassaint, Megan Hamm

JMIR Hum Factors 2025;12:e73719

Developing and Evaluating a Bundled Digital Tool to Improve Complex Care and Self-Management of Patients With Inflammatory Bowel Disease: Protocol for a Hybrid Effectiveness-Implementation Study

Developing and Evaluating a Bundled Digital Tool to Improve Complex Care and Self-Management of Patients With Inflammatory Bowel Disease: Protocol for a Hybrid Effectiveness-Implementation Study

While a multifaceted approach to the treatment of IBD is encouraged by most international treatment guidelines [9,10], adherence to multifaceted treatment by health care providers (HCPs) remains low [11], for a variety of reasons, including a perceived lack of time during appointments to discuss factors outside of physical symptoms and medications [12]. This low adherence to a widely accepted approach for treatment emphasizes the need for solutions to help close this gap [13].

Kaitlyn Delaney Chappell, Melissa Fox, Thomas Scott Armstrong, Lekan Ajibulu, Cynthia H Seow, Aldo Montano-Loza, Karen I Kroeker, Gilaad G Kaplan, Kerri Novak, Christopher Ma, Richard Ingram, Frank Hoentjen, Brendan Halloran, Farhad Peerani, Dina Kao, Karen Wong

JMIR Res Protoc 2025;14:e65659

Role and Use of Race in Artificial Intelligence and Machine Learning Models Related to Health

Role and Use of Race in Artificial Intelligence and Machine Learning Models Related to Health

The role and use of the social construct of race within health-related artificial intelligence (AI) and machine learning (ML) models have become a subject of increased attention and controversy. As noted in the National Academies’ recent report “Ending Unequal Treatment,” it is increasingly clear that race in all its complexity is a powerful predictor of unequal treatment and health care outcomes [1].

Martin C Were, Ang Li, Bradley A Malin, Zhijun Yin, Joseph R Coco, Benjamin X Collins, Ellen Wright Clayton, Laurie L Novak, Rachele Hendricks-Sturrup, Abiodun O Oluyomi, Shilo Anders, Chao Yan

J Med Internet Res 2025;27:e73996

eHealth Literacy and Participation in Remote Blood Pressure Monitoring Among Patients With Hypertension: Cross-Sectional Study

eHealth Literacy and Participation in Remote Blood Pressure Monitoring Among Patients With Hypertension: Cross-Sectional Study

Hypertension has remained a public health concern in the American adult population. Hypertension, defined as systolic blood pressure (BP) ≥130 mm Hg or diastolic BP ≥80 mm Hg or both, has a prevalence of 46.7%, and control (systolic BP Over the years, several models and scales of e-HL have been proposed to measure e-HL [6-20]. There is currently no gold standard for e-HL measurement.

Chinwe E Eze, Michael P Dorsch, Antoinette B Coe, Corey A Lester, Lorraine R Buis, Karen B Farris

J Med Internet Res 2025;27:e71926

Data Collection for Automatic Depression Identification in Spanish Speakers Using Deep Learning Algorithms: Protocol for a Case-Control Study

Data Collection for Automatic Depression Identification in Spanish Speakers Using Deep Learning Algorithms: Protocol for a Case-Control Study

This might lead to a potential bias if recordings of both classes were done in different rooms (ie, recording participants with depression in a clinic and those with depression in an office or studio) as room acoustics have a significant impact on voice recordings [18].

Luis F Brenes, Luis A Trejo, Jose Antonio Cantoral-Ceballos, Daniela Aguilar-De León, Fresia Paloma Hernández-Moreno

JMIR Res Protoc 2025;14:e60439

Validation and Acceptability of the Mobile App Version of the Control of Allergic Rhinitis and Asthma Test for Children (CARATKids): Cross-Sectional Study

Validation and Acceptability of the Mobile App Version of the Control of Allergic Rhinitis and Asthma Test for Children (CARATKids): Cross-Sectional Study

Allergic rhinitis, another common condition, often develops early in life, with a prevalence of 8.5% at ages 6‐7, rising to 14.6% in those aged 13‐14 years old [6]. The symptoms of allergic rhinitis have a profound negative impact on children’s physical and emotional health, sleep quality, and daily activities [7].

Dulce Abreu da Mata, Inês Pais-Cunha, Sandra Catarina Ferraz, Daniela da Rocha Couto, Catarina Ferraz, Sónia Silva, José Carlos Valente, Pedro Vieira-Marques, João A Fonseca, Inês Azevedo, Cristina Jácome

JMIR Pediatr Parent 2025;8:e73531