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Authors’ Response to Peer Reviews of “Improving Tuberculosis Detection in Chest X-Ray Images Through Transfer Learning and Deep Learning: Comparative Study of Convolutional Neural Network Architectures”

Authors’ Response to Peer Reviews of “Improving Tuberculosis Detection in Chest X-Ray Images Through Transfer Learning and Deep Learning: Comparative Study of Convolutional Neural Network Architectures”

This is the authors’ response to peer-review reports for “Improving Tuberculosis Detection in Chest X-Ray Images Through Transfer Learning and Deep Learning: Comparative Study of Convolutional Neural Network Architectures.” The paper [2] presents a comprehensive overview of the methods and results but can benefit from clearer transitions between sections. For instance, adding brief connecting sentences at the end of each section would help guide the reader into the next topic.

Alex Mirugwe, Lillian Tamale, Juwa Nyirenda

JMIRx Med 2025;6:e77221

Peer Review of “Improving Tuberculosis Detection in Chest X-Ray Images Through Transfer Learning and Deep Learning: Comparative Study of Convolutional Neural Network Architectures”

Peer Review of “Improving Tuberculosis Detection in Chest X-Ray Images Through Transfer Learning and Deep Learning: Comparative Study of Convolutional Neural Network Architectures”

This is a peer-review report for “Improving Tuberculosis Detection in Chest X-Ray Images Through Transfer Learning and Deep Learning: Comparative Study of Convolutional Neural Network Architectures.” The manuscript [1] presents a study that evaluates the performance of various convolutional neural network architectures—namely, VGG16, VGG19, Res Net50, Res Net101, Res Net152, and Inception-Res Net-V2—in classifying chest x-ray images to detect tuberculosis (TB).

Natthapong Nanthasamroeng

JMIRx Med 2025;6:e77174

Peer Review of “Improving Tuberculosis Detection in Chest X-Ray Images Through Transfer Learning and Deep Learning: Comparative Study of Convolutional Neural Network Architectures”

Peer Review of “Improving Tuberculosis Detection in Chest X-Ray Images Through Transfer Learning and Deep Learning: Comparative Study of Convolutional Neural Network Architectures”

This is a peer-review report for “Improving Tuberculosis Detection in Chest X-Ray Images Through Transfer Learning and Deep Learning: Comparative Study of Convolutional Neural Network Architectures.” The paper [1] presents a comprehensive overview of the methods and results but can benefit from clearer transitions between sections. For instance, adding brief connecting sentences at the end of each section would help guide the reader into the next topic.

Rapeepan Pitakaso

JMIRx Med 2025;6:e77171

Improving Tuberculosis Detection in Chest X-Ray Images Through Transfer Learning and Deep Learning: Comparative Study of Convolutional Neural Network Architectures

Improving Tuberculosis Detection in Chest X-Ray Images Through Transfer Learning and Deep Learning: Comparative Study of Convolutional Neural Network Architectures

Tuberculosis (TB) remains one of the leading infectious diseases worldwide, affecting an estimated one-third to one-fourth of the global population with the bacillus Mycobacterium tuberculosis, the causative agent of TB [1]. In 2019, it was estimated that over 10 million individuals globally contracted TB; yet, only 71% were detected, diagnosed, and reported through various countries’ national TB programs, leaving approximately 29% of cases unreported [2].

Alex Mirugwe, Lillian Tamale, Juwa Nyirenda

JMIRx Med 2025;6:e66029

Analyzing Satellite Imagery to Target Tuberculosis Control Interventions in Densely Urbanized Areas of Kigali, Rwanda: Cross-Sectional Pilot Study

Analyzing Satellite Imagery to Target Tuberculosis Control Interventions in Densely Urbanized Areas of Kigali, Rwanda: Cross-Sectional Pilot Study

Tuberculosis (TB) is one of the major global health challenges that could be managed through prompt diagnosis and treatment initiation. An estimated 10.6 million people became ill, and 1.6 million people died from TB in 2021 [1]. Despite international efforts, the burden of disease remains uncontrolled in many of the most fragile communities around the world.

Mauro Faccin, Caspar Geenen, Michiel Happaerts, Sien Ombelet, Patrick Migambi, Emmanuel André

JMIR Public Health Surveill 2025;11:e68355

Understanding Providers’ Attitude Toward AI in India’s Informal Health Care Sector: Survey Study

Understanding Providers’ Attitude Toward AI in India’s Informal Health Care Sector: Survey Study

Tuberculosis (TB) remains a significant global health challenge, with over 80% of reported cases and deaths originating from low- and middle-income countries (LMICs) worldwide [1]. Among these countries, India shoulders a substantial burden, accounting for a quarter of all TB cases and resulting in approximately 89,000 deaths in the year 2019 alone [2]. The COVID-19 pandemic further worsened these global inequalities, particularly by disrupting TB diagnostic and treatment services [3,4].

Sumeet Kumar, Snehil Rayal, Raghuram Bommaraju, Navya Pratyusha Varasala, Sirisha Papineni, Sarang Deo

JMIR Form Res 2025;9:e54156

Effectiveness of a Mobile Health Intervention (DOT Selfie) in Increasing Treatment Adherence Monitoring and Support for Patients With Tuberculosis in Uganda: Randomized Controlled Trial

Effectiveness of a Mobile Health Intervention (DOT Selfie) in Increasing Treatment Adherence Monitoring and Support for Patients With Tuberculosis in Uganda: Randomized Controlled Trial

The End TB Strategy envisions a world free of tuberculosis (TB), with zero deaths, disease, and suffering due to TB by 2035 [1]. In 2022, an estimated 10.6 million new cases were reported, while 1.6 million people died from TB worldwide [2]. Although effective treatments for TB disease have existed for over 50 years, nonadherence to medication remains a common problem among patients and poses a significant obstacle to achieving the goals of the End TB Strategy [1,3].

Juliet Nabbuye Sekandi, Esther Buregyeya, Sarah Zalwango, Damalie Nakkonde, Patrick Kaggwa, Trang Ho Thu Quach, David Asiimwe, Lynn Atuyambe, Kevin Dobbin

JMIR Mhealth Uhealth 2025;13:e57991

Interventions to Maintain HIV/AIDS, Tuberculosis, and Malaria Service Delivery During Public Health Emergencies in Low- and Middle-Income Countries: Protocol for a Systematic Review

Interventions to Maintain HIV/AIDS, Tuberculosis, and Malaria Service Delivery During Public Health Emergencies in Low- and Middle-Income Countries: Protocol for a Systematic Review

The findings from this review will inform the development of national and global guidance on the maintenance of services for HIV/AIDS, tuberculosis, and malaria during public health emergencies. What interventions have been implemented to maintain the delivery of HIV/AIDS, tuberculosis, and malaria services during public health emergencies in low- and middle-income countries?

Steven Ndugwa Kabwama, Rhoda K. Wanyenze, Helena Lindgren, Neda Razaz, John M Ssenkusu, Tobias Alfvén

JMIR Res Protoc 2025;14:e64316

The Use of “Cancer Ratio” in Differentiating Malignant and Tuberculous Pleural Effusions: Protocol for a Prospective Observational Study

The Use of “Cancer Ratio” in Differentiating Malignant and Tuberculous Pleural Effusions: Protocol for a Prospective Observational Study

Previously published studies in India have revealed tuberculosis and malignancy to be common causes of exudative pleural effusion in India [2-5]. The implications of tuberculosis and malignancy being the cause of pleural effusion are strikingly different. The diagnosis of tubercular pleural effusion (TPE) indicates a potentially curable disease. In contrast, a malignant pleural effusion (MPE) is evidence of an advanced stage of malignancy with incurability and a poor prognosis [6].

Sai Pooja Chalamalasetty, Preetam Acharya, Thomas Antony, Anand Ramakrishna, Himani Kotian

JMIR Res Protoc 2024;13:e56592

Analysis of Tuberculosis Epidemiological Distribution Characteristics in Fujian Province, China, 2005-2021: Spatial-Temporal Analysis Study

Analysis of Tuberculosis Epidemiological Distribution Characteristics in Fujian Province, China, 2005-2021: Spatial-Temporal Analysis Study

Tuberculosis (TB), a chronic infectious disease, has been endangering human health over the years. In Europe, in the 17th and 18th centuries, TB was known as the “white plague,” infecting almost 100% of the population and killing 25% of the population [1,2]. As one of the high-burden countries, Chinese TB control still needs to be strengthened [3]. Over the years, TB incidence has shown a downward trend year by year.

Shanshan Yu, Meirong Zhan, Kangguo Li, Qiuping Chen, Qiao Liu, Laurent Gavotte, Roger Frutos, Tianmu Chen

JMIR Public Health Surveill 2024;10:e49123