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Evaluation of the Digital Support Tool Gro Health W8Buddy as Part of Tier 3 Weight Management Service: Observational Study

Evaluation of the Digital Support Tool Gro Health W8Buddy as Part of Tier 3 Weight Management Service: Observational Study

Overweight and obesity are more prevalent in people living in the most deprived areas compared to the least deprived areas (72% and 58%, respectively) [1]. Similarly, excess weight disproportionately affects people in the Black ethnic group (72% compared to 64% in people from the White ethnic group) [1]. People living with obesity are at increased risk of chronic diseases (eg, type 2 diabetes mellitus [T2 DM], cancer, and mental illnesses) and have reduced life expectancy [2].

Petra Hanson, Farah Abdelhameed, Mohammed Sahir, Nick Parsons, Arjun Panesar, Michaela de la Fosse, Charlotte Summers, Amit Kaura, Harpal Randeva, Vinod Menon, Thomas M Barber

J Med Internet Res 2025;27:e62661

The Role of Mobile Apps in Obesity Management: Systematic Review and Meta-Analysis

The Role of Mobile Apps in Obesity Management: Systematic Review and Meta-Analysis

In the United States, projections show that by 2050, the number of adults who are overweight or obese will increase from 172 million in 2021 to 213 million. This trend not only affects health care spending, with direct costs potentially reaching up to US $481 billion in 2016, but also leads to higher indirect costs due to lower productivity and work incapacity.

Carmelo Pujia, Yvelise Ferro, Elisa Mazza, Samantha Maurotti, Tiziana Montalcini, Arturo Pujia

J Med Internet Res 2025;27:e66887

The Impact of Technology-Enabled Medical Nutrition Therapy on Weight Loss in Adults With Overweight and Obesity: Retrospective Observational Study

The Impact of Technology-Enabled Medical Nutrition Therapy on Weight Loss in Adults With Overweight and Obesity: Retrospective Observational Study

This study aimed to evaluate the effectiveness of this combined solution on weight loss among adults with overweight and obesity across the United States. Nourish is a national telehealth provider of MNT delivered by a licensed RD, paired with a companion mobile app to offer asynchronous support and tools. Nourish has a network of over 1500 RDs covering all major specialties, including overweight and obesity, diabetes, and heart disease, and can serve patients across all 50 states.

Emily A Hu, Tommy Kelley, Ajay Haryani

JMIR Mhealth Uhealth 2025;13:e70228

Acceptability of and Willingness to Use Virtual Reality Exergames for Weight Loss Among Young Adults With Overweight or Obesity in China: Qualitative Study

Acceptability of and Willingness to Use Virtual Reality Exergames for Weight Loss Among Young Adults With Overweight or Obesity in China: Qualitative Study

In 2025, more than 3041 million adults will be overweight (42% of the population), and 1249 million will be diagnosed with obesity (17% of the population) [3]. Especially, obesity prevalence among young adults ranged from 2.3% to 12%, and overweight was 28.8% [4]. Young adults (aged 18‐25 years) are considered a “vulnerable group” prone to adopting unhealthy lifestyles that can lead to overweight and obesity [5,6].

Yanya Chen, Bingsheng Guan, Yaqi Zhang, Suen Chow Lee, Jia-yu Liu, Sicun Li, Ming Liu, Xiaoshen Zhang, Wai-kit Ming

JMIR Serious Games 2025;13:e66998

Large-Scale Evaluation and Liver Disease Risk Prediction in Finland’s National Electronic Health Record System: Feasibility Study Using Real-World Data

Large-Scale Evaluation and Liver Disease Risk Prediction in Finland’s National Electronic Health Record System: Feasibility Study Using Real-World Data

The burden of liver disease increases yearly in Finland because the Finnish population age average grows, and obesity and overweight are more common problems in the Finnish population [1]. On average, there are 1000 deaths caused by alcoholic liver disease every year [2]. For the early detection of individuals from the general population at high risk for future severe liver disease, the CLiv D (Chronic Liver Disease score) score was developed.

Viljami Männikkö, Janne Tommola, Emmi Tikkanen, Olli-Pekka Hätinen, Fredrik Åberg

JMIR Med Inform 2025;13:e62978

Interactive Effects of Weight Recording Frequency and the Volume of Chat Communication With Health Care Professionals on Weight Loss in mHealth Interventions for Noncommunicable Diseases: Retrospective Observational Study

Interactive Effects of Weight Recording Frequency and the Volume of Chat Communication With Health Care Professionals on Weight Loss in mHealth Interventions for Noncommunicable Diseases: Retrospective Observational Study

It was found that 43% of individuals aged 18 years and older were overweight and 16% were living with obesity in 2022 over the world [1,2]. Several guidelines for primary and secondary prevention of NCDs recommend weight loss for managing risk factors derived from insulin resistance [3-6].

Yuta Hagiwara, Takuji Adachi, Masashi Kanai, Kotoe Shimizu, Shinpei Ishida, Takahiro Miki

Interact J Med Res 2025;14:e65863

Healthy Mom Zone Adaptive Intervention With a Novel Control System and Digital Platform to Manage Gestational Weight Gain in Pregnant Women With Overweight or Obesity: Study Design and Protocol for a Randomized Controlled Trial

Healthy Mom Zone Adaptive Intervention With a Novel Control System and Digital Platform to Manage Gestational Weight Gain in Pregnant Women With Overweight or Obesity: Study Design and Protocol for a Randomized Controlled Trial

Guidelines from the Institutes of Medicine (IOM) [1] and National Academy of Medicine [2] recommend that the optimal total GWG should be based on a woman’s prepregnancy BMI category (ie, overweight: 6.8-11.3 kg; obese: 5.0-9.1 kg). However, evidence from a meta-analytic review including over 1 million pregnant women found that nearly 50% of women exceeded their recommended goals [9], and this was prevalent among those with normal weight as well as those with overweight or obesity.

Danielle Symons Downs, Abigail M Pauley, Daniel E Rivera, Jennifer S Savage, Amy M Moore, Danying Shao, Sy-Miin Chow, Constantino Lagoa, Jaimey M Pauli, Owais Khan, Allen Kunselman

JMIR Res Protoc 2025;14:e66637

High-Intensity Interval Training for Individuals With Isolated Impaired Fasting Glucose: Protocol for a Proof-of-Concept Randomized Controlled Trial

High-Intensity Interval Training for Individuals With Isolated Impaired Fasting Glucose: Protocol for a Proof-of-Concept Randomized Controlled Trial

This is a “proof-of-concept” 1:1 parallel-group RCT involving 34 physically inactive individuals aged 35-65 years who are overweight or obese and have i-IFG. Figure 2 presents the study’s CONSORT diagram. The Georgia Clinical Research Center (GCRC) at Emory University Hospital will serve as the site for participant recruitment and conducting study procedures. A highly trained and experienced study coordinator will recruit participants through a comprehensive 3-step screening procedure.

Sathish Thirunavukkarasu, Thomas R Ziegler, Mary Beth Weber, Lisa Staimez, Felipe Lobelo, Mindy L Millard-Stafford, Michael D Schmidt, Aravind Venkatachalam, Ram Bajpai, Farah El Fil, Maria Prokou, Siya Kumar, Robyn J Tapp, Jonathan E Shaw, Francisco J Pasquel, Joe R Nocera

JMIR Res Protoc 2025;14:e59842

Body Fat and Obesity Rates, Cardiovascular Fitness, and the Feasibility of a Low-Intensity Non–Weight-Centric Educational Intervention Among Late Adolescents: Quasi-Experimental Study

Body Fat and Obesity Rates, Cardiovascular Fitness, and the Feasibility of a Low-Intensity Non–Weight-Centric Educational Intervention Among Late Adolescents: Quasi-Experimental Study

Global estimates suggest that the overall prevalence of childhood overweight and obesity could reach 30% by 2030, with boys (34.2%) surpassing girls (27.4%) [2]. This trend is particularly alarming in middle- and high-income countries, where childhood overweight and obesity rates are projected to reach 58.3% by 2030 [2]. In Saudi Arabia, the obesity epidemic has mirrored global trends, with a marked increase in prevalence among both adults and adolescents.

Areeg Zuair, Fahad M Alhowaymel, Rola A Jalloun, Naif S Alzahrani, Khalid H Almasoud, Majdi H Alharbi, Rayan K Alnawwar, Mohammed N Alluhaibi, Rawan S Alharbi, Fatima M Aljohan, Bandar N Alhumaidi, Mohammad A Alahmadi

JMIR Pediatr Parent 2025;8:e67213