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Lactogenesis, the process by which the mammary glands develop and regulate milk secretion, is a complex physiological process involving an orchestrated series of endocrine and autocrine/paracrine hormonal changes. The secretory activation stage (known as lactogenesis II) is tightly related to effective breastfeeding with frequent and adequate milk removal from the breast [10]; therefore, this stage can be dramatically perturbed by the introduction of nonmother’s milk feeds [4].
JMIR Pediatr Parent 2023;6:e43837
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