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Feasibility, Acceptability, and Potential Effects of a Digital Oral Anticancer Agent Intervention: Protocol for a Pilot Randomized Controlled Trial

Feasibility, Acceptability, and Potential Effects of a Digital Oral Anticancer Agent Intervention: Protocol for a Pilot Randomized Controlled Trial

As OAA development and use expands, medication adherence issues related to OAAs are increasingly of interest to multiple stakeholders, including policy makers, insurance companies, drug makers, health care providers, and researchers [25]. A systematic review of factors influencing adherence to oral anticancer drugs identified three potentially modifiable factors that interventions should address: (1) side effects and toxicities, (2) forgetfulness, and (3) the lack of timely information [26].

Saima Ahmed, Christine Maheu, Walter Gotlieb, Gerald Batist, Carmen G Loiselle

JMIR Res Protoc 2025;14:e55475

Mental Health Providers’ Challenges and Solutions in Prescribing Over Telemedicine: Content Analysis of Semistructured Interviews

Mental Health Providers’ Challenges and Solutions in Prescribing Over Telemedicine: Content Analysis of Semistructured Interviews

The US Drug Enforcement Administration extended prescribing flexibilities past the May 11, 2023, PHE deadline and is in the process of finalizing a rule regarding telemedicine prescribing [4,5]. There has been concern that waiving elements of the Ryan Haight Act, which previously required providers to meet with patients in person before prescribing certain controlled substances, would adversely impact patient outcomes [6,7].

Julia Ivanova, Mollie R Cummins, Hiral Soni, Triton Ong, Brian E Bunnell, Esteban López, Brandon M Welch

JMIR Hum Factors 2025;12:e65419

Telemedicine Prescribing by US Mental Health Care Providers: National Cross-Sectional Survey

Telemedicine Prescribing by US Mental Health Care Providers: National Cross-Sectional Survey

Pursuant to the Ryan Haight Act, the US Drug Enforcement Agency (DEA) required that health care providers conduct an in-person evaluation of patients, before prescribing controlled substances via telemedicine. This measure was intended to prevent health care providers from prescribing potentially harmful medications with only minimal and inadequate online interaction with a patient.

Mollie R Cummins, Julia Ivanova, Hiral Soni, Zoe Robbins, Brian E Bunnell, Esteban López, Brandon M Welch

JMIR Form Res 2025;9:e63251

Simulation of Contraceptive Access for Adolescents and Young Adults Using a Pharmacist-Staffed e-Platform: Development, Usability, and Pilot Testing Study

Simulation of Contraceptive Access for Adolescents and Young Adults Using a Pharmacist-Staffed e-Platform: Development, Usability, and Pilot Testing Study

Safety concerns indicated educational information presented needs to not only address contraception concerns but also inform AYA of the pharmacist’s credibility and remind future users that pharmacists provide medical care already, such as vaccine delivery and drug interaction information [23]. Limitations of this study include the small sample size, single-city site, and limited rounds of usability testing. In addition, current state policy allows only for the simulation of pharmacist prescriptions.

Kayla Knowles, Susan Lee, Sophia Yapalater, Maria Taylor, Aletha Y Akers, Sarah Wood, Nadia Dowshen

JMIR Pediatr Parent 2025;8:e60315

Self-Reported Side Effects Associated With Selective Androgen Receptor Modulators: Social Media Data Analysis

Self-Reported Side Effects Associated With Selective Androgen Receptor Modulators: Social Media Data Analysis

However, no SARM has received US Food and Drug Administration approval to date. Studies show SARMs are associated with acute hepatotoxicity [2], and recent case reports indicate long-term testosterone suppression along with nephrotoxicity and cardiotoxicity [3,4]. Abuse of SARMs has become increasingly prevalent due to targeting of both athletes and youth through social media platforms.

Aditya Joshi, Diego Federico Kaune, Phillip Leff, Emily Fraser, Sarah Lee, Morgan Harrison, Moustafa Hazin

J Med Internet Res 2025;27:e65031

An Analysis of the Prevalence and Trends in Drug-Related Lyrics on Twitter (X): Quantitative Approach

An Analysis of the Prevalence and Trends in Drug-Related Lyrics on Twitter (X): Quantitative Approach

The prevalence of user-generated drug abuse content on social media platforms has been well-documented [14]. These extensive datasets of online drug-related communications have emerged as a primary source, allowing researchers to interpret human behaviors, identify patterns, and analyze evolving drug cultures [15,16].

Waylon Luo, Ruoming Jin, Deric Kenne, NhatHai Phan, Tang Tang

JMIR Form Res 2024;8:e49567

Impact of Changes in Criminal-Legal Practices During the COVID-19 Pandemic on the HIV Risk Behaviors of Women Who Use Drugs: Protocol for a Multimethods Qualitative Study

Impact of Changes in Criminal-Legal Practices During the COVID-19 Pandemic on the HIV Risk Behaviors of Women Who Use Drugs: Protocol for a Multimethods Qualitative Study

Women who use illicit drugs are also disproportionately impacted by HIV: 16% of newly diagnosed women in 2019 attributed the transmission to injection drug use and women who use drugs are more likely to report high-risk sexual behavior [2-6].

Amy B Smoyer

JMIR Res Protoc 2024;13:e58285

Investigating Older Adults’ Perceptions of AI Tools for Medication Decisions: Vignette-Based Experimental Survey

Investigating Older Adults’ Perceptions of AI Tools for Medication Decisions: Vignette-Based Experimental Survey

However, up to one-half of older adults take at least 1 inappropriate medication, which can lead to drug-drug interactions, adverse events, additional medical appointments, emergency department visits, functional decline, reduced quality of life, and increased health care costs [3]. Older adults frequently report that they prefer to participate in shared decision-making [4].

Sarah E Vordenberg, Julianna Nichols, Vincent D Marshall, Kristie Rebecca Weir, Michael P Dorsch

J Med Internet Res 2024;26:e60794

Medication Management Initiatives Using Wearable Devices: Scoping Review

Medication Management Initiatives Using Wearable Devices: Scoping Review

According to Clinical Trials.gov, the number of clinical trials using WDs as outcome measures in drug-related interventions increased from 5, between January 1, 2016, and December 31, 2016, to 21 by 2021, marking a more than fourfold increase [21].

Haru Iino, Hayato Kizaki, Shungo Imai, Satoko Hori

JMIR Hum Factors 2024;11:e57652