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Hospitalization and Mortality in Brazilian Children and Adolescents Due to COVID-19: Retrospective Study

Hospitalization and Mortality in Brazilian Children and Adolescents Due to COVID-19: Retrospective Study

COVID-19 is currently one of the most important medical challenges as it affects the entire population, with children and adolescents being infected as easily as adults; children and adolescents often remain asymptomatic or have mild complaints due to their immature immune systems [1].

Ana Carolina Pereira de Godoy, Reinaldo Bulgarelli Bestetti

JMIR Pediatr Parent 2025;8:e67546

Assessing the Impact of a Telemedicine Program on Caregivers of Children With Complex Chronic Conditions: Pre-Post Intervention Study

Assessing the Impact of a Telemedicine Program on Caregivers of Children With Complex Chronic Conditions: Pre-Post Intervention Study

In high-income countries, children with a complex chronic condition (CCC) represent 0.67%‐5% of the pediatric population; however, they consume up to 40% of total health expenditure, involving a high level of care both in and out of hospital, primary care, and non-health services [5-9]. The prevalence of life-threatening or life-limiting illnesses has increased in recent decades, with an estimated 61.1 per 10,000 children aged 1‐19 years in the United Kingdom.

Aurora Madrid-Rodríguez, María José Peláez-Cantero, Alfonso Lendínez-Jurado, Ana Suárez-Carrasco, Elena Godoy-Molina, Antonia Gámez-Ruiz, Ana Corripio-Mancera, Yolanda Ramón-Telo, Ana García-Ruiz, Isabel Leiva-Gea

JMIR Pediatr Parent 2025;8:e62953

Parents’ Motivations for Calling an Out-of-Hours Helpline: Qualitative Study

Parents’ Motivations for Calling an Out-of-Hours Helpline: Qualitative Study

Young children often fall ill, leading to more out-of-hours health care usage compared with other patient age groups [1-3]. Fortunately, severe illness in children is rare [4]. In a study of 16,000 children under 5 years admitted to a pediatric department with fever, only 7% had a severe infection [5]. The high rate of health care usage is often driven by a fear of making the wrong decisions and failing to recognize severe symptoms, particularly in young children [5-10].

Liv Borch-Johnsen, Fredrik Folke, Marianne Sjølin Frederiksen, Morten Schrøder, Gorm Greisen, Stine Lund, Vibeke Zoffmann, Caroline Gren, Tine Tjørnhøj-Thomsen, Dina Cortes

J Med Internet Res 2025;27:e66780

Discriminative Power of the Serious Game Attention Slackline in Children and Adolescents With and Without Attention-Deficit/Hyperactivity Disorder: Validation Study

Discriminative Power of the Serious Game Attention Slackline in Children and Adolescents With and Without Attention-Deficit/Hyperactivity Disorder: Validation Study

This disorder represents one of the most common causes of conduct problems among children [9,11]. In this sense, children with a diagnosis of ADHD may experience a significant deterioration in psychological, social, and academic well-being [12,13]. Given its high prevalence, associated comorbidities, and chronic nature, ADHD represents a major public health concern. [14,15].

Nicolás Ruiz-Robledillo, Ignacio Lucas, Rosario Ferrer-Cascales, Natalia Albaladejo-Blázquez, Javier Sanchis, Juan Trujillo

JMIR Serious Games 2025;13:e65170

The Prevalence of Hypertension Among Children and Antihypertensive Use: Protocol for a Systematic Review and Meta-Analysis

The Prevalence of Hypertension Among Children and Antihypertensive Use: Protocol for a Systematic Review and Meta-Analysis

Globally, confirmed HT is prevalent in 2%-4% of children [6]—as also demonstrated in the United States (2.2%-3.9%) [7]. Whereas in the African and Asian continents, the pooled prevalence of HT among children is 5.5% (Africa) [8], 18.4% (China) [9], and 29.8% (India) [10].

Nur Hasnah Maamor, Nur Ain Zahidah Zainudin, Nur Liana Md Nasir, Kasturi Manoharan, Sharifah Zawani Syed Ahmad Yunus, Nor Asiah Muhamad, Lai Nai Ming

JMIR Res Protoc 2025;14:e65807

Effectiveness of Serious Games as Digital Therapeutics for Enhancing the Abilities of Children With Attention-Deficit/Hyperactivity Disorder (ADHD): Systematic Literature Review

Effectiveness of Serious Games as Digital Therapeutics for Enhancing the Abilities of Children With Attention-Deficit/Hyperactivity Disorder (ADHD): Systematic Literature Review

Title and abstract screening Participants, Intervention, Comparison, Outcomes, Study design (PICOS) diagram for children with attention-deficit/hyperactivity disorder (ADHD) game interventions (2010-2024). The systematic review screening process for ADHD children game studies is based on the PICOS framework. Children diagnosed with ADHD. Studies that did not only include children with ADHD and/or their caregivers (guardians, teachers, and clinicians). Nonhuman studies.

Jing Lin, Woo-Rin Chang

JMIR Serious Games 2025;13:e60937

Game Design, Effectiveness, and Implementation of Serious Games Promoting Aspects of Mental Health Literacy Among Children and Adolescents: Systematic Review

Game Design, Effectiveness, and Implementation of Serious Games Promoting Aspects of Mental Health Literacy Among Children and Adolescents: Systematic Review

A recent survey on health behavior in school-age children in Austria [16] showed that a substantial proportion of those aged 11 to 17 years (31% of the girls and 24% of the boys) reported low levels of self-efficacy. Furthermore, mental health literacy seemed to be particularly low, with only approximately half of those aged 11 to 17 years reporting that they knew where to find support for themselves or relatives in the event of mental health problems [16].

Michael Zeiler, Sandra Vögl, Ursula Prinz, Nino Werner, Gudrun Wagner, Andreas Karwautz, Natalie Zeller, Lorenz Ackermann, Karin Waldherr

JMIR Ment Health 2025;12:e67418

Reasons for Crown Failures in Primary Teeth: Systematic Review and Meta-Analysis

Reasons for Crown Failures in Primary Teeth: Systematic Review and Meta-Analysis

Dental caries is a highly prevalent chronic disease affecting millions of children worldwide, leading to pain, infection, and difficulties in eating and speaking [1-3]. Untreated caries of the primary teeth may affect over 621 million children globally [1]. Early intervention with fillings is essential to manage caries, but in cases where the tooth structure is significantly compromised, pediatric dental crowns become necessary to preserve the tooth’s functionality and prevent premature loss [4].

Stephan Lampl, Deepa Gurunathan, Deepak Mehta, Krithikadatta Jogikalmat

Interact J Med Res 2025;14:e57958

Readdressing the Ongoing Challenge of Missing Data in Youth Ecological Momentary Assessment Studies: Meta-Analysis Update

Readdressing the Ongoing Challenge of Missing Data in Youth Ecological Momentary Assessment Studies: Meta-Analysis Update

For example, a recent study applied EMA in such marginalized minority groups as asylum-seeking children [177], while other EMA protocols were scaled to public implementation [26], where any app-store user could become a participant but would receive only minimal participant care [9,19]. Although such pioneering work may suffer from more missing data, it is not necessarily poorly conducted regarding the valuable insights it offers.

Konstantin Drexl, Vanisha Ralisa, Joëlle Rosselet-Amoussou, Cheng K Wen, Sébastien Urben, Kerstin Jessica Plessen, Jennifer Glaus

J Med Internet Res 2025;27:e65710

Mobile Health Interventions for Modifying Indigenous Maternal and Child–Health Related Behaviors: Systematic Review

Mobile Health Interventions for Modifying Indigenous Maternal and Child–Health Related Behaviors: Systematic Review

Studies were excluded if they reported on the development or design of a digital health intervention without reporting on its effectiveness on the behavioral outcomes of Indigenous women and children, reported on mixed Indigenous and non-Indigenous populations without reporting subgroup data, or applied the intervention directly to children with the intention to change maternal behavior.

Sana Ishaque, Ola Ela, Anna Dowling, Chris Rissel, Karla Canuto, Kerry Hall, Niranjan Bidargaddi, Annette Briley, Claire T Roberts, Billie Bonevski

J Med Internet Res 2025;27:e57019