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Skip search results from other journals and go to results- 3 JMIR Medical Informatics
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We sincerely appreciate your thoughtful and constructive comments on our recent paper exploring noninvasive anemia diagnosis through facial visible light reflectance spectroscopy and machine learning [1,2]. Your attention and insightful suggestions greatly guide our efforts to enhance this work. We address your key points below, offering clarifications as needed. You noted that uncontrolled factors like smoking and nutrition might influence anemia severity and spectral data.
JMIR Med Inform 2025;13:e74333
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The Anemia Risk Warning Model Based on a Noninvasive Method: Key Insights and Clarifications
We recently read with great interest the article by Zhang et al [1], which presents a noninvasive technique for diagnosing anemia using facial visible light reflectance spectroscopy, combined with machine learning (ML) algorithms for predictive modeling. Anemia is a widespread public health issue affecting over 1.7 billion people, with symptoms including fatigue and cognitive decline [2].
JMIR Med Inform 2025;13:e73297
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The global prevalence of anemia in 2019 was 39.8% in children aged 6‐59 months, with 269 million children having anemia, while in Malaysia, the prevalence of anemia was 24.6% in children of the same age [5]. In Malaysia, the current prevalence of anemia is approximately 46.5% among children, and 1 in 3 children (
Iron deficiency can occur without anemia; this occurs when the iron store is depleted while the individual is still having normal Hb levels.
JMIR Pediatr Parent 2025;8:e58586
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According to the results of China’s fourth nutritional survey, the prevalence of anemia among Chinese residents is 20.1%, and the global prevalence of anemia in all ages is 22.8% in 2019 [4], indicating it has become an important public health issue. In a survey of 13,175 Chinese adults aged >50 years, the prevalence of anemia is 31%, indicating that anemia is particularly prevalent in China’s middle-aged and older adult population [5].
JMIR Med Inform 2025;13:e64204
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Blood Management: A Current Opportunity in Perioperative Medicine
This is a complex approach that focuses on three pillars: (1) optimizing patient hematopoiesis and enhancing red cell mass, (2) minimizing blood losses with improved source control and optimization of coagulopathy, and (3) enhancing patient tolerance to anemia [2].
JMIR Perioper Med 2024;7:e57012
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However, anemia has been identified as a modifiable risk factor for poor perioperative outcomes [8,9]. Preoperative anemia is relatively common, affecting 25% to 75% of patients with an increasing prevalence in older patients and those with cancer [10,11]. Consequently, the relationship between anemia and perioperative transfusion provides a related risk for perioperative morbidity and mortality [12-15].
JMIR Perioper Med 2023;6:e49186
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3: Long-term event-free survival, chimerism and fertility outcomes in 234 patients with sickle-cell anemiaanemia
JMIR Res Protoc 2022;11(7):e36780
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Preoperative optimization is fundamental to improving surgical outcomes, with correction or improvement in iron deficiency anemia (IDA) being an important aspect in the preoperative management of patients undergoing major elective surgery [1]. This has resulted in a large drive across the United Kingdom for developing perioperative iron infusion pathways.
Interact J Med Res 2022;11(1):e31082
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mHealth for Anemia Reduction: Protocol for an Entertainment Education–Based Dual Intervention
Anemia diminishes work productivity [3,4], increases the risk of adverse birth outcomes [5], and hinders the healthy development of children of pregnant mothers with anemia [6]. It is often not explicitly identified by women, but they do report high levels of fatigue [3]. The reduction in anemia through normative innovations (RANI) project [2] investigates the potential of an adaptive, multilevel social norms–based behavior change intervention to reduce anemia among women of reproductive age in Odisha.
JMIR Res Protoc 2021;10(11):e26252
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Reference 54: Improved hydroxyurea effect with the use of text messaging in children with sickle cell anemia the effect of mobile-directly observed therapy on adherence to hydroxyurea in adults with sickle cell anemiaanemia
J Med Internet Res 2018;20(7):e10940
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