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Safety Evaluation in Healthy Adults of Motion-Based Virtual Reality Dichoptic Training for Pediatric Patients With Amblyopia: Prospective Intervention Study

Safety Evaluation in Healthy Adults of Motion-Based Virtual Reality Dichoptic Training for Pediatric Patients With Amblyopia: Prospective Intervention Study

Previous studies on VR games for amblyopia primarily focused on nonengaging content, such as passive image viewing or using conventional consumer game controllers, which underuse the full potential of VR technology to enhance hand-eye coordination [16-18]. Children with amblyopia typically exhibit reduced hand-eye coordination [21,22]; however, its improvement with amblyopia treatment has not been widely established.

Masakazu Hirota, Yuichi Okumura, Ken Nagino, Takao Hayashi, Takashi Negishi, Shintaro Nakao, Hitoshi Kawasaki, Takenori Inomata

JMIR Form Res 2025;9:e69801

Transformative Gamified Binocular Therapy for Unilateral Amblyopia in Young Children: Pilot Prospective Efficacy and Safety Study

Transformative Gamified Binocular Therapy for Unilateral Amblyopia in Young Children: Pilot Prospective Efficacy and Safety Study

Amblyopia refers to a unilateral or bilateral decrease of vision caused by abnormal vision development in childhood. It is a common cause of visual impairment in children, significantly affecting their social environment and quality of life. Studies indicate that amblyopia affects 0.7%-2.6% of children aged 30‐71 months and 1%-5.5% of older children [1-3]. Anisometropia is linked to a higher risk of developing amblyopia, with about one-third of children with amblyopia displaying this condition [4].

Wenqing Zhu, Shuneng Gu, Jian Li, Jin Lin, Chanling Hu, Rui Liu

JMIR Serious Games 2025;13:e63384

ChatGPT and Google Assistant as a Source of Patient Education for Patients With Amblyopia: Content Analysis

ChatGPT and Google Assistant as a Source of Patient Education for Patients With Amblyopia: Content Analysis

Amblyopia is a global public health problem with multiple impacts on vision and quality of life [1]. Amblyopia, if untreated, leads to permanent visual impairment in adults. The underlying causes are undiscovered anisometropia (unequal refractive error between the 2 eyes), visual deprivation such as congenital or juvenile cataracts, or strabismus with anisometropia. Treatment can be as simple as a pair of glasses.

Gloria Wu, David A Lee, Weichen Zhao, Adrial Wong, Rohan Jhangiani, Sri Kurniawan

J Med Internet Res 2024;26:e52401

Gamification to Support Adherence to a Therapeutic Ambylopia Treatment for Children: Retrospective Study Using a Focal Ambient Visual Acuity Stimulation Game

Gamification to Support Adherence to a Therapeutic Ambylopia Treatment for Children: Retrospective Study Using a Focal Ambient Visual Acuity Stimulation Game

Unilateral amblyopia is a developmental disorder resulting in degraded visual acuity in 1 eye. During the developmental phase of vision, degraded stimulation by the weaker eye leads to the underdevelopment of the corresponding cortical visual areas [1]. Amblyopia is associated with poor binocular visual experience in children and has a lasting effect on the individuals’ quality of life, while children with amblyopia are impacted in their daily activities and future job selection [2].

Catheline Bocqué, Jingyun Wang, Annekatrin Rickmann, Henrike Julich-Haertel, Uwe Kaempf, Kai Januschowski

JMIR Pediatr Parent 2023;6:e32282

Deep Learning–Based Prediction of Refractive Error Using Photorefraction Images Captured by a Smartphone: Model Development and Validation Study

Deep Learning–Based Prediction of Refractive Error Using Photorefraction Images Captured by a Smartphone: Model Development and Validation Study

Amblyopia is the most common cause of permanent visual impairment in children, and its worldwide prevalence is estimated to be approximately 1.6%-5% [1,2]. Refractive error is one of the leading causes of pediatric amblyopia [3].

Jaehyeong Chun, Youngjun Kim, Kyoung Yoon Shin, Sun Hyup Han, Sei Yeul Oh, Tae-Young Chung, Kyung-Ah Park, Dong Hui Lim

JMIR Med Inform 2020;8(5):e16225

Effect of Peripheral Defocus on Axial Eye Growth and Modulation of Refractive Error in Hyperopes: Protocol for a Nonrandomized Clinical Trial

Effect of Peripheral Defocus on Axial Eye Growth and Modulation of Refractive Error in Hyperopes: Protocol for a Nonrandomized Clinical Trial

Uncorrected hyperopia can cause blurring of distance vision and near vision and is a known risk factor for the development of strabismus and amblyopia [1]. There is a growing body of evidence that uncorrected hyperopia, in addition to visual consequences, may have a negative impact on educational attainment [2,3] and visuocognitive and visuomotor skills [4].

Ian G Beasley, Leon N Davies, Nicola S Logan

JMIR Res Protoc 2018;7(9):e173