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Extended Reality (XR) in Pediatric Acute and Chronic Pain: Systematic Review and Evidence Gap Map
patient and clinician voices in developing tools to address pain related school impairment: a phase I
JMIR Pediatr Parent 2025;8:e63854
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Patients in the VR group completed the Gold-Rizzo Immersion and Presence (GRIP) inventory, which is a 16-item measure that asks the patients to indicate their degree of immersion in the game, with 0 indicating no immersion, 1 indicating little immersion, and 2 indicating a lot of immersion. This measure is comprised of 3 domains—sense of involvement, perceived realism of the VR game, and sense of transportation into the experience [30].
J Med Internet Res 2024;26:e53196
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Several systematic reviews and meta-analyses of virtual reality–based exposure therapy (VRET) for anxiety disorders have shown that VRET is equal or superior to the gold standard of in vivo exposure for anxiety reduction [19-23].
Overall, there is support for using VR and AR as a tool to reduce perceptions of pain intensity in the context of procedural pain, including evidence of effects for children and adolescents.
J Med Internet Res 2021;23(4):e25916
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The VR experience also made patients more comfortable in the hospital, with 1 patient, when asked his favorite part of the game, saying, “I liked the patient going to sleep, so [the patient] didn’t feel any pain.” This response demonstrates the power of familiarizing pediatric patients with their upcoming procedures, putting them at ease for when the time for the procedure comes. Doc VR also made patients feel “Good” and “Happy.”
J Med Internet Res 2021;23(4):e25504
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