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Data Integrity Issues With Web-Based Studies: An Institutional Example of a Widespread Challenge
JMIR Ment Health 2024;11:e58432
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For example, author Rennick-Egglestone, who is a longstanding member of a mental health support group for people experiencing cyclothymia, has seen peers leave the group permanently when researchers join to share recruitment material, due to a fear that group interactions may be treated as data in research studies. The British Sociological Association has published general guidance on researching web-based forums, which provides a broad overview of thought and practice in this space [26].
J Med Internet Res 2024;26:e58939
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For the NEON-O trial, the SD of the MANSA scores for the study population was estimated from baseline data provided by the first 350 enrolled participants (see the study by Rennick-Egglestone et al [27] for the rationale). A total sample size of 994 was selected to provide 90% power to detect a minimal clinically important effect size (Cohen d) of 0.27 (SD 0.94; power=90%; P=.05), allowing for 40% attrition, which was estimated from the completion rates for interim data.
JMIR Ment Health 2024;11:e45754
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