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We determined that an aerobic exercise training dose of approximately 2400 minutes (40 h) over 6 months would be necessary for CMH benefits. We then spread the minutes across a 24-week intervention period for this trial with wheelchair users to ensure adequate time to safely and progressively reach the prescribed dose. The session structure and exercise minutes for each week are presented in Table 1, and the intervention components are summarized in Table 2.
JMIR Res Protoc 2025;14:e57423
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