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Text-Messaging, Online Peer Support Group, and Coaching Strategies to Optimize the HIV Prevention Continuum for Youth: Protocol for a Randomized Controlled Trial

Text-Messaging, Online Peer Support Group, and Coaching Strategies to Optimize the HIV Prevention Continuum for Youth: Protocol for a Randomized Controlled Trial

YAHR are difficult to identify and intervene with in medical clinics because most youth (about 60% of general adolescent population) do not access health care [8-10]. Adolescents typically fail to disclose their sexual behaviors to their families or their physicians, most often because they are never asked about risk [11-13].

Dallas Swendeman, Elizabeth Mayfield Arnold, Danielle Harris, Jasmine Fournier, W Scott Comulada, Cathy Reback, Maryann Koussa, Manuel Ocasio, Sung-Jae Lee, Leslie Kozina, Maria Isabel Fernández, Mary Jane Rotheram, Adolescent Medicine Trials Network (ATN) CARES Team

JMIR Res Protoc 2019;8(8):e11165

Strategies to Treat and Prevent HIV in the United States for Adolescents and Young Adults: Protocol for a Mixed-Methods Study

Strategies to Treat and Prevent HIV in the United States for Adolescents and Young Adults: Protocol for a Mixed-Methods Study

A set of 3 interrelated studies, known as the Comprehensive Adolescent Research and Engagement Studies (CARES), is being mounted to evaluate strategies to increase youth’s uptake, maintenance, and retention in the HIV Prevention and Treatment Continua [2-4]. Participants are acutely infected YLH, YLH with established HIV infection, and YHR. This paper summarizes the rationale behind these studies, including the recruitment, retention, assessment, and intervention strategies common across them.

Mary Jane Rotheram, Maria Isabel Fernandez, Sung-Jae Lee, Sue Ellen Abdalian, Leslie Kozina, Maryann Koussa, Warren Scott Comulada, Jeffrey D Klausner, Elizabeth Mayfield Arnold, Manuel A Ocasio, Dallas Swendeman, Adolescent Medicine Trials Network (ATN) CARES Team

JMIR Res Protoc 2019;8(1):e10759

Acute HIV Infection in Youth: Protocol for the Adolescent Trials Network 147 (ATN147) Comprehensive Adolescent Research and Engagement Studies (CARES) Study

Acute HIV Infection in Youth: Protocol for the Adolescent Trials Network 147 (ATN147) Comprehensive Adolescent Research and Engagement Studies (CARES) Study

To further demonstrate the effectiveness of early antiretroviral therapy on infants, a large multicenter phase 3 trial, National Institute of Child Health and Development HIV Prevention Trials Network 040, conducted by our team of investigators revealed that c ART reduced intrapartum HIV transmission by 50% [19] in high-risk HIV-exposed infants whose mothers did not receive c ART during pregnancy.

Karin Margit Nielsen-Saines, Kate Mitchell, Tara Kerin, Jasmine Fournier, Leslie Kozina, Brenda Andrews, Ruth Cortado, Robert Bolan, Risa Flynn, Mary Jane Rotheram, Sue Ellen Abdalian, Yvonne Bryson, Adolescent Medicine Trials Network (ATN) CARES Team

JMIR Res Protoc 2019;8(1):e10807

Development of an Electronic Data Collection System to Support a Large-Scale HIV Behavioral Intervention Trial: Protocol for an Electronic Data Collection System

Development of an Electronic Data Collection System to Support a Large-Scale HIV Behavioral Intervention Trial: Protocol for an Electronic Data Collection System

This paper fills in gaps in the literature by describing the EDC system from an ongoing HIV biobehavioral intervention trial, Adolescent Medicine Trials Network “Comprehensive Adolescent Research & Engagement Studies” (ATN CARES), and highlights the benefits and limitations of what current EDC systems can provide. We begin with an overview of EDC system functionality and highlight salient features for behavioral intervention trials.

W Scott Comulada, Wenze Tang, Dallas Swendeman, Amy Cooper, Jeremy Wacksman, Adolescent Medicine Trials Network (ATN) CARES Team

JMIR Res Protoc 2018;7(12):e10777