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Normothermic Versus Hypothermic Cardiopulmonary Bypass in Children Undergoing Open Heart Surgery (Thermic-2): Study Protocol for a Randomized Controlled Trial

Normothermic Versus Hypothermic Cardiopulmonary Bypass in Children Undergoing Open Heart Surgery (Thermic-2): Study Protocol for a Randomized Controlled Trial

Supportive of this notion are clinical studies in adults [16] in which normothermic CPB (35°C-37°C) was associated with significantly elevated levels of inflammatory markers compared to hypothermic CPB (28°C-30°C).

Sarah Baos, Karen Sheehan, Lucy Culliford, Katie Pike, Lucy Ellis, Andrew J Parry, Serban Stoica, Mohamed T Ghorbel, Massimo Caputo, Chris A Rogers

JMIR Res Protoc 2015;4(2):e59