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Trust and Privacy Concerns Among Cancer Survivors Who Did Not Visit a Research Website Offering Free Genetic Counseling Services for Families: Survey Study

Trust and Privacy Concerns Among Cancer Survivors Who Did Not Visit a Research Website Offering Free Genetic Counseling Services for Families: Survey Study

Participants were compensated with US $10 as an incentive to complete the survey. The first item was prefaced by a statement saying that in the past few months, the GCR mailed the survivor a packet of information about a study called “Your Family Connects.” The statement explained that the packet included a US $5 bill and several pages of information about how recipients and their family could access an informational website about inherited risk for ovarian cancer.

James A Shepperd, Colleen M McBride, Weihua An, Jingsong Zhao, Rebecca D Pentz, Cam Escoffery, Kevin Ward, Yue Guan

J Med Internet Res 2025;27:e64228

Online Health Information–Seeking Behaviors Among the Chongqing Population: Cross-Sectional Questionnaire Study

Online Health Information–Seeking Behaviors Among the Chongqing Population: Cross-Sectional Questionnaire Study

This metropolis is an ideal context for understanding situation of OHIS in western China. The study objectives were to (1) determine the prevalence, common topics, and methods of OHIS in the Chongqing population and (2) identify the factors that influence the OHIS behaviors of this population. This research may help improve ways of promoting efficient and appropriate OHIS for users and harnessing the benefits of the internet as a source of health information.

Honghui Rong, Lu Lu, Miao He, Tian Guo, Xian Li, Qingliu Tao, Yixin Li, Chuanfen Zheng, Ling Zhang, Fengju Li, Dali Yi, Enyu Lei, Ting Luo, Qinghua Yang, Ji-an Chen

JMIR Form Res 2025;9:e56028

Effect of Immersive Virtual Reality Teamwork Training on Safety Behaviors During Surgical Cases: Nonrandomized Intervention Versus Controlled Pilot Study

Effect of Immersive Virtual Reality Teamwork Training on Safety Behaviors During Surgical Cases: Nonrandomized Intervention Versus Controlled Pilot Study

In VR, the audience becomes an integral part of the story rather than merely an onlooker. The advantages of immersive VR primarily include: (1) viewers are placed within a 360-degree environment, where each movement of the head unveils new dimensions of the scene.

Lukasz Mazur, Logan Butler, Cody Mitchell, Shaian Lashani, Shawna Buchanan, Christi Fenison, Karthik Adapa, Xianming Tan, Selina An, Jin Ra

JMIR Med Educ 2025;11:e66186

The rs243865 Polymorphism in Matrix Metalloproteinase-2 and its Association With Target Organ Damage in Patients With Resistant Hypertension: Cross-Sectional Study

The rs243865 Polymorphism in Matrix Metalloproteinase-2 and its Association With Target Organ Damage in Patients With Resistant Hypertension: Cross-Sectional Study

Renal damage was defined as an albumin-to-creatinine ratio of: normal to mildly increased (300 mg/g). Patients with a history of CKD stage 4 or 5, or renal failure (estimated glomerular filtration rate Vascular stiffness was assessed using pulse wave velocity (PWV), defined as the speed at which arterial pressure waves move along the vessel wall, with a PWV >10 m/s being indicative of vascular damage via the BOSO ABI-100 system.

An Tuan Huynh, Hoang Anh Vu, Ho Quoc Chuong, Tien Hoang Anh, An Viet Tran

JMIR Cardio 2025;9:e71016

Use of Retrieval-Augmented Large Language Model for COVID-19 Fact-Checking: Development and Usability Study

Use of Retrieval-Augmented Large Language Model for COVID-19 Fact-Checking: Development and Usability Study

The COVID-19 pandemic has been accompanied by an “infodemic,” characterized by the rapid spread of misinformation and disinformation, significantly undermining public health efforts [1]. Misinformation refers to the unintentional spread of incorrect or misleading information [2], while disinformation involves deliberately disseminating false information to deceive [3].

Hai Li, Jingyi Huang, Mengmeng Ji, Yuyi Yang, Ruopeng An

J Med Internet Res 2025;27:e66098

Mobile Health–Based Motivational Interviewing to Promote SARS-CoV-2 Vaccination in Rural Adults: Protocol for a Pilot Randomized Controlled Trial

Mobile Health–Based Motivational Interviewing to Promote SARS-CoV-2 Vaccination in Rural Adults: Protocol for a Pilot Randomized Controlled Trial

Near-universal smartphone ownership provides an ideal yet untapped mechanism to deliver MI-based vaccine interventions to rural populations. In summary, there is a critical need for improving SARS-Co V-2 vaccination rates among rural populations in Oklahoma and nationwide. To address this need, we will test the efficacy of an m Health-based MI intervention to diminish SARS-Co V-2 vaccine hesitancy (MOTIVACC).

Ashlea Braun, Sarah Corcoran, Khue Tu Doan, Cameron Jernigan, Cate Moriasi, Michael Businelle, Thanh Bui

JMIR Res Protoc 2025;14:e64010

Challenges for Data Quality in the Clinical Data Life Cycle: Systematic Review

Challenges for Data Quality in the Clinical Data Life Cycle: Systematic Review

In this study, an EHR refers to all electronically stored records of patient health information, encompassing both electronic medical records and personal health records. To conduct the literature review, we followed the methods of previous studies that closely reviewed previous EHR data [14,27-29]. A Pub Med literature search was conducted by the first author in October 2023.

Doyeon An, Minsik Lim, Suehyun Lee

J Med Internet Res 2025;27:e60709

Playful Antisedentary Interactions for Online Meeting Scenarios: A Research Through Design Approach

Playful Antisedentary Interactions for Online Meeting Scenarios: A Research Through Design Approach

To further clarify the insights from the idea cards, we used an affinity diagram to identify common themes, patterns, and relationships among the data points. For the discussion content, we used the conventional qualitative content analysis method outlined by Hsieh and Shannon [59] to examine how the initial design considerations supported participants in formulating their ideas. An illustration of our design process, highlighting the various stages involved. The co-design workshops yielded rich insights.

Jiaqi Jiang, Shanghao Li, Xian Li, Yingxin Xu, Jian Zhao, Pengcheng An

JMIR Serious Games 2025;13:e62778

Efficacy of a Web-Based Integrated Growth Mindset Intervention on Reducing Anxiety Among Social Work and Counseling Practicum Trainees: Protocol for a 2-Arm Randomized Controlled Trial

Efficacy of a Web-Based Integrated Growth Mindset Intervention on Reducing Anxiety Among Social Work and Counseling Practicum Trainees: Protocol for a 2-Arm Randomized Controlled Trial

Practicum is an essential educational component of professional training [1,2], bridging the gap between theory and practice and enhancing the professional capacity and core competence of future practitioners [3,4]. The quality of fieldwork profoundly influences social work trainees’ personal, intellectual, and professional development [4], per communication skills, critical reflection, professional growth, creativity, innovation, and self-efficacy [1,5].

Yongyi Wang, An Xi, Stella S K Wong, Kong Yam, Janet Tsin Yee Leung, Shimin Zhu

JMIR Res Protoc 2025;14:e67234