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Impact of Mānuka Honey on Symptoms and Quality of Life in Individuals With Functional Dyspepsia: Protocol for a Feasibility Randomized Controlled Trial

Impact of Mānuka Honey on Symptoms and Quality of Life in Individuals With Functional Dyspepsia: Protocol for a Feasibility Randomized Controlled Trial

Nanopore-generated sequence reads, which are re-base-called using “Super high accuracy base-calling” post run, will be passed through Fast QC and then the standard EPI2 ME amplicon workflow using the SILVA-138 database for taxonomic assignment. As a preliminary investigation into the postprandial absorption and excretion of selected mānuka honey-derived compounds, a randomized, crossover, acute study involving 6 healthy participants without symptoms of FD was conducted.

Laura Ombasa, Jody Miller, Lara Ware, Holly Abbotts-Holmes, Jeffry Tang, Olivier Gasser, Karl Fraser, Simone Bayer, Roslyn Kemp, Rory Costello, Andrew Highton, Jackie Evans, Troy Merry, Michael Schultz, Chris Frampton, Richard Gearry, Warren McNabb, Nicole Roy

JMIR Res Protoc 2025;14:e66417