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Size and Composition of Caregiver Networks Who Manage Medications for Persons Living With Dementia: Cross-Sectional Analysis of the 2011-2022 National Health and Aging Trends Study

Size and Composition of Caregiver Networks Who Manage Medications for Persons Living With Dementia: Cross-Sectional Analysis of the 2011-2022 National Health and Aging Trends Study

Among non-Hispanic White caregivers who manage medications (n=1633), the mean number of participants assisting with medications was 2.4 (range 1-9). Caregivers who helped with medications were 17.3% (282/1633) spouses, 33.9% (555/1633) children, 2.9% (48/1633) grandchildren, 9.6% (157/1633) others, 35.5% (580/1633) paid helpers, and 0.7% (11/1633) siblings. Among Black or African American caregivers (n=799), the mean number of caregivers assisting with medications was 2.8 (range 1-9).

Reed WR Bratches, Frank Puga, Paul J Barr, Amanda N Leggett, Meredith Masel, James Nicholas Odom, Rita Jablonski

Interact J Med Res 2025;14:e64499

Toward a Domain-Overarching Metadata Schema for Making Health Research Studies FAIR (Findable, Accessible, Interoperable, and Reusable): Development of the NFDI4Health Metadata Schema

Toward a Domain-Overarching Metadata Schema for Making Health Research Studies FAIR (Findable, Accessible, Interoperable, and Reusable): Development of the NFDI4Health Metadata Schema

The majority of these resources were studies (n=243), data dictionaries (n=143), questionnaires (n=78), substudies (n=49), and other data collection instruments (n=35). Remaining resources included datasets (n=19), manuals of operations (SOPs; n=15), other study documents (n=15), registries or secondary data sources (n=9), case report forms (n=5), codebooks (n=5), interview schemes and themes (n=4), data management plans (n=3), other resource types (n=2), and statistical analysis plans (n=1).

Haitham Abaza, Aliaksandra Shutsko, Sophie A I Klopfenstein, Carina N Vorisek, Carsten Oliver Schmidt, Claudia Brünings-Kuppe, Vera Clemens, Johannes Darms, Sabine Hanß, Timm Intemann, Franziska Jannasch, Elisa Kasbohm, Birte Lindstädt, Matthias Löbe, Katharina Nimptsch, Ute Nöthlings, Marisabel Gonzalez Ocanto, Tracy Bonsu Osei, Ines Perrar, Manuela Peters, Tobias Pischon, Ulrich Sax, Matthias B Schulze, Florian Schwarz, Carolina Schwedhelm, Sylvia Thun, Dagmar Waltemath, Hannes Wünsche, Atinkut A Zeleke, Wolfgang Müller, Martin Golebiewski

JMIR Med Inform 2025;13:e63906

Types of HPV Vaccine Misinformation Circulating on Twitter (X) That Parents Find Most Concerning: Insights From a Cross-Sectional Survey and Content Analysis

Types of HPV Vaccine Misinformation Circulating on Twitter (X) That Parents Find Most Concerning: Insights From a Cross-Sectional Survey and Content Analysis

The caregivers in the study were primarily mothers (n=198, 75%), 67% (n=199) were non-Hispanic White, and 54% (n=142) had a high school education or less. Their children had an average age of 8.96 (SD 0.98) years, and 49% (n=128) were male and 51% (n=135) female (Table 1). Participant characteristics (N=263). Demographic information from a cross-sectional Internet survey of 263 US caregivers.

Jennifer C Morgan, Sarah Badlis, Katharine J Head, Gregory Zimet, Joseph N Cappella, Melanie L Kornides

J Med Internet Res 2025;27:e54657

Effects of the National Institutes of Health Stroke Scale and Modified Rankin Scale on Predictive Models of 30-Day Nonelective Readmission and Mortality After Ischemic Stroke: Cohort Study

Effects of the National Institutes of Health Stroke Scale and Modified Rankin Scale on Predictive Models of 30-Day Nonelective Readmission and Mortality After Ischemic Stroke: Cohort Study

Of these 5808 hospitalizations, 794 (13.7%) were excluded from the study analysis because the patient died during the index hospitalization (n=198, 3.4%), the hospitalization originated at a non-KPNC facility (n=504, 8.7%), or follow-up data was incomplete (n=92, 1.6%). The final study population included 5014 hospitalizations. The average age of the study population was 71.9 (SD 13.99) years and 49.4% (2477/5014) of patients were male.

Mai N Nguyen-Huynh, Janet Alexander, Zheng Zhu, Melissa Meighan, Gabriel Escobar

JMIR Med Inform 2025;13:e69102

Evaluating the Usability, Acceptability, User Experience, and Design of an Interactive Responsive Platform to Improve Perinatal Nurses’ Stigmatizing Attitudes Toward Substance Use in Pregnancy: Mixed Methods Study

Evaluating the Usability, Acceptability, User Experience, and Design of an Interactive Responsive Platform to Improve Perinatal Nurses’ Stigmatizing Attitudes Toward Substance Use in Pregnancy: Mixed Methods Study

Before developing the platform, we conducted 2 focus groups related to the synchronous version of the intervention (n=11) to identify specific requirements for the interactive, responsive platform. Participants noted the need for the adapted intervention to (1) take less time to complete, (2) allow for self-pacing, and (3) be delivered asynchronously [24].

Michael Rubyan, Yana Gouseinov, Mikayla Morgan, Deborah Rubyan, Divya Jahagirdar, David Choberka, Carol J Boyd, Clayton Shuman

JMIR Hum Factors 2025;12:e67685

Podcasts in Mental, Physical, or Combined Health Interventions for Adults: Scoping Review

Podcasts in Mental, Physical, or Combined Health Interventions for Adults: Scoping Review

Following this, 3427 evidence sources were screened for title and abstract (n=3267, 95.33% were excluded). The remaining 160 (4.67%) evidence sources were assessed against the PCC framework for full-text eligibility.

Elizabeth M Dascombe, Philip J Morgan, Ryan J Drew, Casey P Regan, Gabrielle M Turner-McGrievy, Myles D Young

J Med Internet Res 2025;27:e63360

Cognitive Behavioral Immersion for Depression: Protocol for a Three-Arm Randomized Controlled Trial of Peer-Based Coaching in the Metaverse

Cognitive Behavioral Immersion for Depression: Protocol for a Three-Arm Randomized Controlled Trial of Peer-Based Coaching in the Metaverse

Thus, a total sample size of 306 (n=102 in each study arm) will be effective for detecting meaningful differences in outcomes between CBI and the other conditions. This study was funded in September 2023. Recruitment of study participants began in February 2024. As of January 2025, 306 participants have been enrolled. Data collection is expected to be completed by September 2025. Data have not yet been analyzed.

Noah Robinson, Francisco N Ramos, Steven D Hollon, Gloria T Han, Iony D Ezawa

JMIR Res Protoc 2025;14:e65970

SEARCH Study: Text Messages and Automated Phone Reminders for HPV Vaccination in Uganda: Randomized Controlled Trial

SEARCH Study: Text Messages and Automated Phone Reminders for HPV Vaccination in Uganda: Randomized Controlled Trial

Messages included both reminders about the needed dose as well as educational information about the importance of the HPV vaccine and were based on a successful previous study [17], as well as 85 key informant interviews with caregivers (n=30), adolescents (n=30), health care workers (n=11), school (n=10), and government officials (n=4). First, team members identified the key content, timing, and framing for each message based on the interviews.

Sabrina B Kitaka, Joseph Rujumba, Sarah K Zalwango, Betsy Pfeffer, Lubega Kizza, Juliane P Nattimba, Ashley B Stephens, Nicolette Nabukeera-Barungi, Chelsea S Wynn, Juliet N Babirye, John Mukisa, Ezekiel Mupere, Melissa S Stockwell

JMIR Mhealth Uhealth 2025;13:e63527