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A total of 6 (29%) of the 14 external validations assessed discrimination, with all using the c-statistic. Birks et al [21] externally validated Colon Flag at multiple time intervals between the most recent blood test and diagnosis in a UK sample, reporting c-statistic=0.844 at 3‐6 months, which reduced to 0.751 at 23‐36 months [21]. Kinar et al [27] also externally validated the Colon Flag using UK data and reported a similar c-statistic (0.81) at 3‐6 months before colorectal cancer diagnosis [27].
JMIR Cancer 2025;11:e70275
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The rising tide of HIV among young men who have sex with men in Brazil: insights from the Conectad@s
JMIR Public Health Surveill 2025;11:e67005
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Biomarkers will include immune functioning indicators (IL-1β, -6, and -8, tumor necrosis factor-alpha, C-reactive protein, serum amyloid A, vascular cell adhesion molecule 1, and intercellular cell adhesion molecule 1), metabolic functioning indicators (glycosylated hemoglobin, high-density lipoprotein, and low-density lipoprotein cholesterol, and triglycerides), adiposity (BMI, body fat percent, and waist-to-hip ratio), and blood pressure.
JMIR Res Protoc 2025;14:e73070
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The State of Remote Patient Monitoring for Chronic Disease Management in the United States
J Med Internet Res 2025;27:e70422
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development (R)
Acquisition of external graphics designer (G)
Selection of software and metrics (J)
Learning to work with existing technologies for scheduling and publishing (AF)
Sudden unexpected team member change (U)
Outputs
Extracting key teaching points from top PECARN articles into tweet (X)
Tweet frequency established at the same time each week (3 times per week) (AH)
Tweet visual structure: Intentional or strategic polls, emojis, bullet points, and multimedia such as images and videos (AA, AB, AC, C,
JMIR Form Res 2025;9:e59481
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