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Overview of unstructured data processing for a single timestep. CUIs are extracted from clinical notes by c TAKES and assembled into a usable data structure that maps encounter ID to a list of CUIs associated with the timestep. A table of CUI-associated data is created, independent of patient data, containing preferred text, ICD codes, Sap BERT embedding, and cluster information.
J Med Internet Res 2025;27:e75340
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Since cortisol is incorporated into growing hair, hair is emerging as a novel matrix for measuring retrospective cortisol secretion over months [9,11,12]. Each 1 cm hair segment, beginning from the proximal end, approximates a month’s cortisol production.
JMIR Form Res 2025;9:e63811
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Nivel-PCD: All insurance claims codes as recorded by the GP are received, however, when a dataset has been requested by the researcher, the codes are filtered by the data processor to include a selection of codes relevant to the study (in agreement with the researchers), on a database zone level.
Contacts
Defined as moments of contact between a GP and a patient. Based on unique dates on which an insurance claim code was recorded by the GP, that is, the maximum number of contacts per patient per day is 1.
J Med Internet Res 2025;27:e64628
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Addressing care partner needs is a pressing health, economic, and social imperative.
There is a growing literature on web-based peer support networks for care partners of people with serious illness, and such networks typically contain a platform to exchange information and provide peer support [5].
JMIR Form Res 2025;9:e70206
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Exclusion criteria for individuals with MDD included a severe neurodevelopmental disorder or other impairment that impacts the participant’s ability to provide the required information for the study (eg, symptom reports), a substance or medication-induced affective disorder, an affective disorder secondary to a medical condition, and a current Axis I psychotic or bipolar disorder.
JMIR Form Res 2025;9:e66187
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Traditionally, prediction models combine patient demographic, clinical, and treatment characteristics in the form of a statistical or mathematical model, usually regression, classification, or neural networks, but deal with a limited number of predictor variables (usually below 25).
JMIR Cancer 2025;11:e64399
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Chatbots are a highly accessible and scalable platform that allows for simulated conversations. Accessible via the web through a hyperlink or downloadable app, chatbots can be used on a smartphone, tablet, or computer. The use of chatbots has also been shown to improve access to services and support health equity by providing personalized health education, being available in multiple languages, and offering continuous access to information [11-15].
JMIR Cancer 2025;11:e65848
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However, CDD has a distinct genetic cause and symptom profile, as severe developmental delay is exhibited from birth and seizure onset occurs earlier, and it was thus established as a separate clinical condition in 2013 [3-5]. CDD is caused by pathogenic variants in the X-linked gene CDKL5, which plays a key role in normal brain development and function [6].
JMIR Form Res 2025;9:e72489
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To develop a more comprehensive understanding of these challenges, it is essential to analyze posts that involve multiple, overlapping themes and reflect the complexity of real-world experiences.
We address this research gap by proposing a theme-driven framework that provides a labeled dataset. A comprehensive analysis is performed on this dataset, covering multiple themes of TINs and capturing Reddit post data from thousands of affected individuals.
J Med Internet Res 2025;27:e68886
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As the PGHD database evolves and lessons are learned from researchers, field testers, and pilot projects, the goal will be to integrate PGHD into fundamental clinical workflows and build a knowledge base for where integration provides the greatest value.
Data collected in the PGHD database are guided by a series of VHA policy and strategy documents, the development of which was overseen by the Office of Connected Care [9].
J Med Internet Res 2025;27:e70755
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