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Predicting Postoperative Delirium in Older Patients Before Elective Surgery: Multicenter Retrospective Cohort Study

Predicting Postoperative Delirium in Older Patients Before Elective Surgery: Multicenter Retrospective Cohort Study

The study aimed to develop a prediction model in a naturalistic setting. Information regarding interventions was included only as a sensitivity analysis to demonstrate its potential impact on the prediction model. The potential imbalance of the dataset for all models was tested by oversampling with the Synthetic Minority Oversampling Technique [48].

Shun-Chin Jim Wu, Nitin Sharma, Anne Bauch, Hao-Chun Yang, Jasmine L Hect, Christine Thomas, Sören Wagner, Bernd R Förstner, Christine A F von Arnim, Tobias Kaufmann, Gerhard W Eschweiler, Thomas Wolfers, PAWEL Study Group

JMIR Aging 2025;8:e67958

User Archetypes of a Well-Being–Promoting Mobile App Among Adults: Cross-Sectional Study and Cluster Analysis of Usage Patterns

User Archetypes of a Well-Being–Promoting Mobile App Among Adults: Cross-Sectional Study and Cluster Analysis of Usage Patterns

This study was a part of the Feeling Good North Savo program [21]. The aim of the study was to explore the associations between the characteristics of participants and their likelihood of using a mobile app promoting well-being. Our assumption, based on the limited existing evidence, was that women, older people, and employed people—indicating a higher socioeconomic status—would be more interested in trying and using the app.

Hanna Rekola, Tommi Tolmunen, Elina Mattila, Juho Strömmer, Timo A Lakka, Helena Länsimies, Tomi Mäki-Opas

JMIR Mhealth Uhealth 2025;13:e68982

Harm Reduction Contingency Management for Stimulant Use Reduction and Antiretroviral Therapy Adherence in HIV Primary Care: Protocol for an Implementation Effectiveness Study

Harm Reduction Contingency Management for Stimulant Use Reduction and Antiretroviral Therapy Adherence in HIV Primary Care: Protocol for an Implementation Effectiveness Study

Stimulant use disorder continues to rise as a devastating public health issue in the United States, accounting for more than 57,000 deaths in 2022—a near 5-fold increase since 2015 [1] Among people living with HIV, stimulant use is particularly prevalent (>5% to 15% in the general population of people with and 30% in safety-net patient populations living with HIV) and represents a key challenge for maintaining overall health [2-4].

Gabriela Steiner, Stefan Baral, Elise D Riley, Steven Shoptaw, Gabriel Chamie, Kate Roberts, Lauren Suchman, Kelly Knight, Monica Gandhi, Phillip Coffin, Ayesha Appa

JMIR Res Protoc 2025;14:e67292

Optimizing the Postcataract Patient Journey Using AI-Driven Teleconsultation: Prospective Case Study

Optimizing the Postcataract Patient Journey Using AI-Driven Teleconsultation: Prospective Case Study

One week after the first eye surgery, patients received both a Dora-NL1 call and a regular postoperative telephone consultation with a clinician. During the telephone consultations, a standardized set of questions was used to evaluate the patient’s symptoms and identify any necessary management changes.

Joukje C Wanten, Noël J C Bauer, Mohita Chowdhury, Aisling Higham, Nick de Pennington, Frank J H M van den Biggelaar, Rudy M M A Nuijts

JMIR Form Res 2025;9:e72574

Uncovering the Understanding of the Concept of Patient Similarity in Cancer Research and Treatment: Scoping Review

Uncovering the Understanding of the Concept of Patient Similarity in Cancer Research and Treatment: Scoping Review

To underline this need and to provide a current understanding and application of patient similarity in the context of cancer, a scoping review was conducted. This review aims to offer a comprehensive understanding of the current applications and methodologies of patient similarity in cancer research, with the hypothesis that a multilayered perspective is essential for enhancing precision oncology and improving patient outcomes.

Iryna Manuilova, Jan Bossenz, Annemarie Bianka Weise, Dominik Boehm, Marvin Döbel, Silke D Werle, Arsenij Ustjanzew, Niklas Reimer, Cosima Strantz, Philipp Unberath, Patrick Metzger, Thomas Pauli, Susann Schulze, Sonja Hiemer, Irmak Oguztürk, Leila Kamkar, Hans A Kestler, Hauke Busch, Benedikt Brors, Jan Christoph

J Med Internet Res 2025;27:e71906

Automated Extraction of Mortality Information From Publicly Available Sources Using Large Language Models: Development and Evaluation Study

Automated Extraction of Mortality Information From Publicly Available Sources Using Large Language Models: Development and Evaluation Study

When the targeted threshold was not met, the annotation team performed a consensus annotation over each document in a given annotation round, discussed their differences, and updated or clarified the annotation guidelines. Once trained, each annotator independently labeled a subset of a corpus totaling 4200 documents (1050 per source). To assess reliability, 100 additional documents (25 per source) were randomly assigned to all 3 annotators, and an independent IAA was conducted.

Mohammed Al-Garadi, Michele LeNoue-Newton, Michael E Matheny, Melissa McPheeters, Jill M Whitaker, Jessica A Deere, Michael F McLemore, Dax Westerman, Mirza S Khan, José J Hernández-Muñoz, Xi Wang, Aida Kuzucan, Rishi J Desai, Ruth Reeves

J Med Internet Res 2025;27:e71113

Assessing the Feasibility of Using Apple Vision Pro While Performing Medical Precision Tasks: Controlled User Study

Assessing the Feasibility of Using Apple Vision Pro While Performing Medical Precision Tasks: Controlled User Study

These techniques rely on correct depth perception, as they involve inserting a suturing needle into a specific layer of the skin [35], making them ideal for evaluating users’ ability to perceive depth in a simulated environment. A suture training kit [36] was used as the base for performing the sutures. All participants were asked to complete 3 SIS, 3 VMS, and close a 5 cm long wound on the suturing kit using a CSS for each intervention.

Hamraz Javaheri, Vitor Fortes Rey, Paul Lukowicz, Gregor A Stavrou, Jakob Karolus, Omid Ghamarnejad

JMIR XR Spatial Comput 2025;2:e73574

Effects of Acute Time-Restricted Eating on Inflammation in Individuals With Psoriasis: Protocol for a Case-Control, Prospective Study

Effects of Acute Time-Restricted Eating on Inflammation in Individuals With Psoriasis: Protocol for a Case-Control, Prospective Study

Measurements were performed in the morning after a 12-hour fast using indirect calorimetry with the ventilated hood technique with a metabolic cart (Parvomedics, Murray, UT) [13]. After a 12-hour (day 0) and 16-hour (day 4) overnight fast, 1 intravenous catheter was placed in each arm for blood draws upon arrival in the morning. A liquid meal (Boost Plus) was provided to meet 33% of the estimated daily calorie requirements.

Sinibaldo Romero Arocha, Kim Han, Rebecca D Huffstutler, Geethika P Thota, Natalie A Macheret, Amber B Courville, Robert J Brychta, Kong Y Chen, Stephanie T Chung, Laura C Coates, Alexander J Clarke, Michael N Sack

JMIR Res Protoc 2025;14:e74999

Enrollment and Retention Outcomes from the Veterans Health Administration for a Remote Digital Health Study: Multisite Observational Study

Enrollment and Retention Outcomes from the Veterans Health Administration for a Remote Digital Health Study: Multisite Observational Study

VA provides health care at 170 VA Medical Centers and 1380 outpatient sites of care [10] that share a common underlying electronic health record with information rolled up into a national data warehouse. The data warehouse enables linkage of study data collected by RPM or mobile app data with a vast amount of VA clinical, health care usage, and cost data.

Jaclyn A Pagliaro, Lauren K Wash, Ka Ly, Jenny Mathew, Alison Leibowitz, Ryan Cabrera, Jolie B Wormwood, Varsha G Vimalananda

JMIR Form Res 2025;9:e68676

Improving Data Integrity in Samples Obtained From Web-Based Recruitment: Protocol for the Development of a Novel System for Assessing Participant Authenticity in a Remote Longitudinal Cohort Study of Polysubstance Use

Improving Data Integrity in Samples Obtained From Web-Based Recruitment: Protocol for the Development of a Novel System for Assessing Participant Authenticity in a Remote Longitudinal Cohort Study of Polysubstance Use

In this paper, we outline a novel system for authenticating participants recruited remotely via a third-party recruitment company for a longitudinal cohort study examining trajectories of opioid-involved PSU and other health outcomes.

Chavez R Rodriguez, Maya Campbell, Erin E Bonar, Jason E Goldstick, Maureen A Walton, Lewei A Lin, Lara N Coughlin

JMIR Res Protoc 2025;14:e69956