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Development and Systematic Evaluation of a Progressive Web Application for Women With Cardiac Pain: Usability Study

Development and Systematic Evaluation of a Progressive Web Application for Women With Cardiac Pain: Usability Study

At heart (formerly HEARTPA♀N) [29], a self-management progressive web application, was developed for women with CAD using a sequential phased approach recommended by the Medical Research Council (MRC) [30-32]. In phase 1, an integrated mixed methods systematic review was conducted to evaluate the current evidence related to the self-management of cardiac pain and associated symptoms (eg, dyspnea and fatigue) in women [7,29].

Monica Parry, Tony Huang, Hance Clarke, Ann Kristin Bjørnnes, Paula Harvey, Laura Parente, Colleen Norris, Louise Pilote, Jennifer Price, Jennifer N Stinson, Arland O’Hara, Madusha Fernando, Judy Watt-Watson, Nicole Nickerson, Vincenza Spiteri DeBonis, Donna Hart, Christine Faubert

JMIR Hum Factors 2025;12:e57583

Greater Improvements in Vaccination Outcomes Among Black Young Adults With Vaccine-Resistant Attitudes in the United States South Following a Digital Health Intervention: Latent Profile Analysis of a Randomized Control Trial

Greater Improvements in Vaccination Outcomes Among Black Young Adults With Vaccine-Resistant Attitudes in the United States South Following a Digital Health Intervention: Latent Profile Analysis of a Randomized Control Trial

A total of 360 Black young adults were included in this study, of whom 76% (n=272) identified as cisgender or transgender women. The median age was 24 (IQR 21‐27) years, and approximately one-third of participants (n=122) had a bachelor’s degree or higher. Overall vaccine uptake at month 3 was low (n=21) and did not significantly differ between the intervention and control arms (odds ratio [OR] 1.88, 95% CI 0.76 to 4.69).

Noah Mancuso, Jenna Michaels, Erica N Browne, Allysha C Maragh-Bass, Jacob B Stocks, Zachary R Soberano, C Lily Bond, Ibrahim Yigit, Maria Leonora G Comello, Margo Adams Larsen, Kathryn E Muessig, Audrey Pettifor, Lisa B Hightow-Weidman, Henna Budhwani, Marie C D Stoner

JMIR Public Health Surveill 2025;11:e67370

Mental Health Apps Available in App Stores for Indian Users: Protocol for a Systematic Review

Mental Health Apps Available in App Stores for Indian Users: Protocol for a Systematic Review

Features of interactive self-care apps (N=33) were reviewed further, and this exercise showed that less than 10% of the apps incorporated explicit delineation of their scope or initial screening for suitability. Slightly more than one-third of these apps included content aimed at encouraging professional help-seeking when needed or an explicit mention of their theoretical or empirical basis. Challenges for potential users were highlighted [20].

Seema Mehrotra, Ravikesh Tripathi, Pramita Sengupta, Abhishek Karishiddimath, Angelina Francis, Pratiksha Sharma, Paulomi Sudhir, Srikanth TK, Girish N Rao, Rajesh Sagar

JMIR Res Protoc 2025;14:e71071

Methadone Patient Access to Collaborative Treatment: Protocol for a Pilot and a Randomized Controlled Trial to Establish Feasibility of Adoption and Impact on Methadone Treatment Delivery and Patient Outcomes

Methadone Patient Access to Collaborative Treatment: Protocol for a Pilot and a Randomized Controlled Trial to Establish Feasibility of Adoption and Impact on Methadone Treatment Delivery and Patient Outcomes

We evaluate the number of clinics and number of patients, assuming that MPACT intervention reduces this frequency to 45% (n=240), 50% (n=300), and 55% (n=330). The power curves based on independent observations (no cluster effect) are shown in Figure 3. The graph shows that the recruitment of 30 clinics, with 20 patients per clinic, provides greater than 80% power to detect a difference in treatment interruption rates of 66% (control) and 55% (MPACT) with α=.05.

Beth E Meyerson, Alissa Davis, Richard A Crosby, Linnea B Linde-Krieger, Benjamin R Brady, Gregory A Carter, Arlene N Mahoney, David Frank, Janet Rothers, Zhanette Coffee, Elana Deuble, Jonathon Ebert, Mary F Jablonsky, Marlena Juarez, Barbara Lee, Heather M Lorenz, Michael D Pava, Kristen Tinsely, Sana Yousaf

JMIR Res Protoc 2025;14:e69829

Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Maternal Metabolic Health and Mother and Baby Health Outcomes (MAMBO): Protocol of a Prospective Observational Study

Given the anticipated overlap of these conditions, ≈20% (n=90) of women will have at least one maternal metabolic disease of interest (secondary outcome). Study data are collected using paper case report forms. These paper documents will be kept in a locked cupboard accessible only to local research staff. Patient information is collected and stored by the investigators in a confidential REDCap (Research Electronic Data Capture system; Vanderbilt University), with password protection and restricted access.

Sarah A L Price, Digsu N Koye, Alice Lewin, Alison Nankervis, Stefan C Kane

JMIR Res Protoc 2025;14:e72542

Media Framing and Portrayals of Ransomware Impacts on Informatics, Employees, and Patients: Systematic Media Literature Review

Media Framing and Portrayals of Ransomware Impacts on Informatics, Employees, and Patients: Systematic Media Literature Review

News media characteristics (N=48). Full articles are located in Multimedia Appendix 6 by article ID number. Regarding access to electronic systems, EHR patient portals enable patients to view test results, communicate with their care team, schedule appointments, and participate in telehealth visits. Portal use can improve the satisfaction and engagement of both clinicians and patients [46,47].

Atiya Avery, Elizabeth White Baker, Brittany Wright, Ishmael Avery, Dream Gomez

J Med Internet Res 2025;27:e59231

Using Large Language Models to Automate Data Extraction From Surgical Pathology Reports: Retrospective Cohort Study

Using Large Language Models to Automate Data Extraction From Surgical Pathology Reports: Retrospective Cohort Study

We reviewed 102 surgical pathology reports from 102 patients and excluded reports if they were from other organ sites (n=10), benign (n=2), cytopathology (n=5), or outside review (n=1). We included 84 reports for analysis. The study flowchart is shown in Figure 2. Flowchart of the study design and analysis. *The concordance rate was calculated as the total number of concordant answers/total number of answers for each of the 12 medical question answering (MQA).

Denise Lee, Akhil Vaid, Kartikeya M Menon, Robert Freeman, David S Matteson, Michael L Marin, Girish N Nadkarni

JMIR Form Res 2025;9:e64544

A Culturally Tailored Artificial Intelligence Chatbot (K-Bot) to Promote Human Papillomavirus Vaccination Among Korean Americans: Development and Usability Study

A Culturally Tailored Artificial Intelligence Chatbot (K-Bot) to Promote Human Papillomavirus Vaccination Among Korean Americans: Development and Usability Study

Demographic characteristics of focus group participants (N=21). As presented in Table 3, most participants had heard of HPV (19/21, 90.5%) and the HPV vaccine (18/21, 81.8%). Half (11/21, 52.4%) of them had received the HPV vaccine, with 7 (63.6%) of the 11 participants completing all 3 doses. HPVa awareness and vaccination status of focus group participants by sex (N=21). a HPV: human papillomavirus.

Minjin Kim, Ellie Kim, Hyeongsuk Lee, Meihua Piao, Brittany Rosen, Jeroan J Allison, Adrian H Zai, Hoa L Nguyen, Dong-Soo Shin, Jessica A Kahn

Asian Pac Isl Nurs J 2025;9:e71865

Extended Reality (XR) in Pediatric Acute and Chronic Pain: Systematic Review and Evidence Gap Map

Extended Reality (XR) in Pediatric Acute and Chronic Pain: Systematic Review and Evidence Gap Map

A much smaller number of studies (n=6) examined the utility of VR in chronic pain populations including intensive pain rehabilitation (n=1) [112], chronic burn dressing (n=1) [113], chronic musculoskeletal pain (n=1) [114], chronic cancer-related pain (n=2) [115,116], and chronic abdominal pain (n=1) [117]. See Figure 2 for the summary of pain populations included across the studies.

Courtney W Hess, Brittany N Rosenbloom, Giulia Mesaroli, Cristal Lopez, Nhat Ngo, Estreya Cohen, Carley Ouellette, Jeffrey I Gold, Deirdre Logan, Laura E Simons, Jennifer N Stinson

JMIR Pediatr Parent 2025;8:e63854